Issue 161

C&T Round Up for Dec & Jan!

This week, we highlight the features we published in Dec & Jan! Learn about combining phages with antibiotics, scaling up phage production, the new Web3 x science movement, and catch Phage Directory's 2021 reflection and 2022 outlook!

Community digest1alert5updates4jobs2posts

Phage alert

Urgent need for Klebsiella variicola phages for a patient in Germany

January 27, 2022

We are urgently seeking Klebsiella variicola phages for a patient in Germany

Ways to help at this stage:

  • By sending your phages for testing on the patient's strain
  • By receiving the strain and testing your phages
  • By receiving the strain and using it to search for new phages against the organism
  • By offering to prepare phages supplied by others to clinical grade
  • By helping spread the word about this request
  • By providing us with names/email addresses of labs you think we should contact

Please email staff@phage.directory if you can help in any way, or if you would like further details/clarification.

Let’s make a difference, Phage Directory

Phage Therapy

Updates

Clinical trial approval: Pherecydes Pharma obtains ANSM Approval for its PhagoDAIR program, which treats osteoarticular infections of prosthetic joints caused by Staphylococcus aureus.

Clinical TrialPhage Therapy

ACD Pharma is constructing a large-scale phage production plant.

Biotech newsPhage productionPharma

Paper: Staphylococcal phages adapt to new hosts by extensive attachment site variability — Helena Leinweber et al.

Phage attachmentResearch paper

Paper: A new sugar for an old phage: a c-di-GMP-dependent polysaccharide pathway sensitizes Escherichia coli for bacteriophage infection — Benjamin Sellner et al.

Phage biologyResearch paper

Paper: Isolation and characterization of Campylobacter jejuni–specific bacteriophages from Germany and their suitability for use in food production — Severin Michael Steffan et al.

Phage in agriculturePhage in foodResearch paper

Jobs

January 28, 2022

Postdoc in phage engineering: The Hartmann lab at Northwestern University is seeking independent, resourceful postdoc researchers experienced in molecular biology & interested in microbial ecology and infectious disease. Potential projects include development of ecologically inspired molecular therapeutics for infection. Candidates also encouraged to propose research topics of their own related to environmental chemistry, microbiomes.

Phage engineeringPost Doc

January 28, 2022

Postdoc: Join the Talbert Research Group at Iowa State University to work on an NIH-funded project focused on bacteriophage engineering for therapeutic applications.

Engineered phagesPost Doc

January 28, 2022

Postdoc: CSIRO Postdoctoral Fellowship in Phage Therapy Bioinformatics, to develop new technology for phage therapy, in conjunction with the MRFF Frontiers funded Phage Australia project.

BioinformaticsPhage TherapyPost Doc

January 28, 2022

PhD candidate to characterize host-virus mechanisms, investigate the evolutionary processes that led to their emergence, and measure their activity in diverse biomes.

MetagenomicsPhD projectVirus-host Interactions

Community board

Thanks to all who came out to the first iVoM Season 2 event of 2022!

Next: Feb 2 from 2-3 PM CET Topic: Phage application in the One Health approach. Speakers: Dr. Cath Rees, Prof. Mariana Piuri, Prof. Lone Brøndsted.

If you want to join this series, which will run through May, please register at https://ivom.phage.directory — as many of you know, ISVM is asking for a small contribution from senior scientists and industry for access to this series, which will support ISVM’s activities now and in the future.

Phage Directory is a proud partner of this event, and so are the local organizers for VoM 2022, the upcoming in-person/hybrid conference in Portugal July 18-22!

ISVMPhage DirectoryVirtual EventViruses of microbesiVoM

January 28, 2022

Hi, I'm looking for a Staph aureus phage that is either phage K or a close relative. I want to use this in my animal model of diabetic foot ulcer infection. I'm at Flinders University in Australia. Thanks. Peter Speck (peter.speck@flinders.edu.au)

Diabetic foot ulcersSeeking phage for research

In this month's Capsid & Tail Monthly Round Up issue, we're highlighting the five feature articles we published in December and January (a two-for-one special!). Be sure to check them out if you missed them, and let us know if you have thoughts, comments or questions! Reach us anytime by email!