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BX004-A first-in-human trial

A first-in-human, double-blind, placebo-controlled phase 1b/2a trial evaluated nebulized three-phage cocktail BX004-A in nine adults with cystic fibrosis and chronic Pseudomonas aeruginosa infection. The trial met its primary safety and tolerability endpoints.

SourcePhage therapy with nebulized cocktail BX004-A for chronic Pseudomonas aeruginosa infections in cystic fibrosis: a randomized first-in-human trial