Community post

We've known for a while that Vibrio cholerae makes cholera toxin because of a phage, and that the phage's receptor is Vibrio's toxin coregulated pilus (Tcp). But how does the phage actually get in? Here's a new paper by Miguel Gutierrez-Rodarte and colleages from Simon Fraser University in Canada that provides evidence that the tip of the CTX phage interacts with the tip of the pilus, followed by the phage being brought in as the pilus retracts!