Community post

Katie Wiebe (Cytophage Technologies, Inc) and colleagues have outlined a scalable and efficient production strategy for the ETEC phage ‘Phage75’, which accounts for infection load, MOI, temperature, media, harvest time, and host bacteria (they screened variables impacting production in a high throughput OD assay). They demonstrate this works in flasks at 3 scales as well as in the Cellexus CellMaker bioreactor.