Community post
Nichith Ratheesh (Arizona State University) published a preprint on how a member of the oral microbiota can actively transport phages by swarming, leading to disruption of E. coli biofilms. They found that Capnocytophaga gingivalis forms tunnels within the 'prey' (E. coli) biofilm, and when phages are actively delivered, curli fiber-containing E. coli biofilms are no longer protected against phage infection. Their results suggest that active delivery of phages by a self-propelled swarm might improve phage therapy pharmacokinetics.
Topics
| Source | Capsid & Tail #134 |
|---|