Effect of PreforPro® on Urinary and Vaginal Health

Inclusion Criteria: * Female * 18-45 years old premenopausal (period within 6 months) * Nugent score of 4-6 (intermediate) or 7-10 (BV) * Have an ability to collect a clean urine sample * Prescription and over the counter medication unchanged for \> 30 days prior to the study. -Participants who are taking medications as needed (PRN) may be included if they began PRN usage \>30 days prior to baseline * Sexually active status of the participants can be either active or inactive * Participants must agree to use a medically approved method of birth control (e.g. hormonal contraceptives, intrauterine devices, vasectomy/tubal ligation, barrier methods and double-barrier method) and must have negative pregnancy test results at screening and baseline Exclusion Criteria: * Faecal incontinence * History of urinary fistula, bladder or kidney stones, interstitial cystitis, or cystoscopic abnormalities that could be malignant * Neurogenic bladder * A history of currently undergoing immunosuppressive drug therapy, chemotherapy, or radiation therapy * Antibiotic and/or anti-fungal medication used within the last four weeks * Oral probiotic supplement use within 2 weeks prior the study excluding yogurt * Drug abuse * Uncontrolled psychological disorders

• PreforPro oral supplement studied for bacterial vaginosis; product class separated from personalized infection therapy.