Clinical study
Phage Therapy for the Treatment of a Chronic Enterococcus Faecium Periprosthetic Joint Infection
| Status | Not yet recruiting |
|---|---|
| Type | Individual-case protocol |
| Countries | Canada |
| Conditions studied | Periprosthetic Joint Infection |
| Study years | 2025 (estimated)–2026 (estimated) |
| Entry review | 2026-10-03 |
Participation
Check the study record or contact the study team for current recruitment and eligibility.
Study eligibility
Inclusion Criteria: This N-of-1 Phage therapy is designed for one patient who meet the following conditions * Willingness to provide signed and dated informed consent form to participate in the clinical study * Chronic prosthetic joint infection * History of multiple surgical and medication managements with no success Exclusion Criteria: * below 18 years of age
Study description
This purpose of this clinical trial is to evaluate the safety, tolerability and efficacy of a bacteriophage therapy in a patient with a methicillin-susceptible Enterococcus faecium (E. faecium) prosthetic joint infection (PJI) of the hip. We have exhausted all surgical and medical management of PJI for our patient. The phage will be administered to the study patient during a 14 days period via intravenous and intra-articular. The patient will be monitored in clinic for up to 1 year.
Study registrations
| ClinicalTrials.gov | NCT06942624 |
|---|
Recorded study locations (1)
Locations listed in the study record; this does not confirm current recruitment or treatment outside the study. A site label may be older than the overall study status.
Concordia Hospital
Winnipeg, Manitoba, Canada
Recorded site status: Not separately listed. Study location source ↗
Notes from the source review
- Single-patient protocol (target/actual n=1); not a broad recruiting program. Planned completion date has passed while registry status remains nonterminal; recheck with site.
Sources and updates
Entry reviewed . This is the date of our source review, not a confirmation of availability today.
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| Study ID | nct06942624 |
|---|