Jessica Sacher, PhD

Phage Directory (Co-founder); Stanford University (Staff Scientist); Bollyky Lab

I'm a co-founder of Phage Directory and have a PhD in Microbiology from the University of Alberta (I studied Campylobacter phage biology).

For Phage Directory, I help physicians find phages for their patients, and I'm always trying to find new ways to help the phage field grow (especially through connecting people and highlighting awesome stuff I see happening in the field).

I spent 2022-2024 as a postdoc in Jon Iredell's group at Westmead Institute for Medical Research in Sydney, Australia, helping get Phage Australia off the ground. I helped set up workflows for phage sourcing, biobanking, diagnostics, production, purification and QC of therapeutic phage batches, and helped build data collection systems to track everything we did. We treated more than a dozen patients in our first year, and I'm so proud of that!

As of 2024, I joined the Bollyky lab at Stanford University as a Staff Scientist, where I'm focused on building the Stanford Center for Phage Pharmaceuticals. The ‘Phage Pharm’ will be a home for innovative phage pharmacodynamics and phage-immune interactions research, with a focus on translating findings directly to the bedside and back to the bench.

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  1. C&T Round Up for April 2022!This week, we highlight the features we published in April! Catch up on what happened at the last Phage Futures Europe, and learn how to organize your phage biobank data!Issue 173Jessica Sacher
  2. C&T Round Up for March 2022!This week, we highlight the features we published in March! Learn about how to name your phage, how to track your phages, and how to get pheedback from phage peers!Issue 170Jessica Sacher
  3. C&T Round Up for February!This week, we highlight the features we published in Feb — learn about digital phagograms, phageSuisse and the recently held Bacteriophage Therapy Summit!Issue 165Jessica Sacher
  4. Let's focus the power of Web3 on science & biotech's problemsPhage Directory started because Jan (a 'tech person') saw how his skills could help fix inefficiencies in Jessica's field: phage biology. Now, more people like Jan are getting excited to focus on solving problems in science/biology/biotech…Issue 160Jessica Sacher
  5. 2022: Building the Operating System for Phage TherapyGood morning, 2022! We’re extremely proud of our work empowering the community, running events like Evergreen and building Instill. This year, we'll be focused on building the “operating system” for phage therapy. From lab workflows to web…Issue 158Jan Zheng, Jessica Sacher
  6. Reflecting back on 2021It's our last issue of the year! We reflect on what we're especially proud of from this year, and highlight some stats on where we're at as a community! Also: a giant thanks to each of our amazing volunteers!Issue 157Jessica Sacher, Jan Zheng
  7. C&T Round Up for November 2021This week, we highlight the feature articles we published in November! Learn about optimizing the route for phage delivery, single use bioreactor technologies vs. traditional solutions, and phage therapy to combat a shell infection in a sea…Issue 155Jessica Sacher
  8. State of Phage #3: Exploring phage collectionsWe're compiling the results of our State of Phage 2020 Survey, and we're excited to show you a third snapshot of the findings! Today we're focusing on phage collections; which phages are labs collecting, how many do they have of each, and…Issue 147Jan Zheng, Jessica Sacher
  9. Evergreen 2021: Many thanks to all 504 phage phans!Last week, in collaboration with Dr. Betty Kutter and her unstoppable team, we helped run the iconic Evergreen International Phage Meeting — but with a twist — this time it was a hybrid virtual/in-person event! We are overjoyed with how it…Issue 139Jessica Sacher, Elizabeth (Betty) Kutter, Jan Zheng
  10. Raise your impact with Instill ScienceAre your manuscripts meeting their potential? We're launching a new community initiative called Instill Science to help you raise your impact (and get credit for helping your fellow phage community members do the same).Issue 134Jessica Sacher, Jan Zheng
  11. You're invited to the Evergreen International Phage Meeting!In case you haven't heard, the Evergreen Phage Meeting is happening both in person and online this year in Olympia, Washington from Aug 1-6. This week, we're highlighting what to expect from this meeting (via a letter from Betty Kutter) and…Issue 133Jessica Sacher
  12. C&T Round Up for May 2021This week, we're highlighting the three feature articles we published in May: a 'behind-the-paper' guest post by Steven Sutcliffe and Michael Shamash, a full recap of all six iVoM webinars by Ivone Martins and Luis Melo, and an interview…Issue 128Jessica Sacher
  13. C&T Round Up for April 2021This week, we're highlighting the four feature articles we published in April: virtual event recaps by volunteers Rohit Kongari and Stephanie Lynch, a guide on responding to phage therapy requests, and an opinion piece by Mert Selimoglu on…Issue 124Jessica Sacher
  14. How to respond when someone asks you for phage therapyAre you getting phage therapy requests from the public, and wondering how to respond? We've put together a guide + resources you can use (short version: send them our way)! Bonus: we've included resources for physicians too, including how…Issue 121Jessica Sacher
  15. Phage Futures Congress 2021: Meeting RecapWe attended Kisaco Research's Phage Futures Congress 2021 at the end of February, and now present our recap of the event. We hope to provide a window into what you missed, and/or a refresher if you were there!Issue 117Jessica Sacher, Sheetal Patpatia, Jan Zheng
  16. Quick Dive: Diabetic foot ulcers and phage therapyToday we're doing a quick dive into diabetic foot ulcers and phages. What's the problem, what are some ways phages have been used to date, and what's the current status of clinical trials?Issue 116Jessica Sacher
  17. C&T Round Up for February 2021This week, we're highlighting the four feature articles we published in February: an interview with Richard Alm of CARB-X, part two of our State of Phage survey results, and a recap of the three phage events we hosted last week, written by…Issue 115Jessica Sacher
  18. State of Phage #2: A wide diversity of strainsWe're compiling the results of our State of Phage 2020 Survey, and we're excited to show you a second snapshot of the findings! Today we're focusing on strain collections; which bacterial species are phage labs collecting, how many do they…Issue 113Jan Zheng, Jessica Sacher
  19. Funding phage development — a Q&A with CARB-X's Richard AlmThis week, we bring you an interview with Dr. Richard Alm, Alliance Director at CARB-X, a major current funder of new antimicrobials, including phage! Richard shares how he sees phages fitting into the clinical landscape, and shares his…Issue 112Jessica Sacher, Richard Alm
  20. State of Phage #1: A wide diversity of backgrounds & phage experienceIt's been almost three months since we launched our State of Phage 2020 Survey! We're excited to show you a snapshot of the data coming in. Today we're focusing on who responded to the survey: where are they from, what's their career stage,…Issue 110Jessica Sacher, Jan Zheng